RESEARCH CONFIRMS IDIOPATHIC HYPERSOMNIA WITH LONG SLEEP NOT THE SAME DISORDER AS WITHOUT LONG SLEEP
The terms "with long sleep" and "without long sleep" never did adequately describe the two forms of Idiopathic Hypersomnia. However did the ICSD3 (International Classification of Sleep Disorders, third edition) get it right by simply combining the two into one? Not according to the recent thorough cluster analysis produced by Karel Šonka, Marek Šusta and Michel Billiard, Narcolepsy with and without cataplexy, idiopathic hypersomnia with and without long sleep time: a cluster analysis. This analysis supports the findings of previous studies that suggest Polysymptomatic Hypersomina (previously referred to as with long sleep) is in fact distinct and unique and is therefore an independent sleep disorder of Monosymptomatic Hypersomnia (previously referred to as without long sleep). The research also showed, which has been the long held belief of many researchers, that the clinical features of Monosymptomatic Hypersomnia are more closely related to those found in Narcolepsy without cataplexy (Type 2 Narcolepsy) and that those two disorders should be merged into one single condition.
"Highlights from the study:
•Hierarchical cluster analysis reviewed the classification of central hypersomnias.
•Narcolepsy with cataplexy and idiopathic hypersomnia with long sleep time constituted independent clusters.
•Narcolepsy without cataplexy and idiopathic hypersomnia without long sleep time entered into the same cluster.
•Narcolepsy without cataplexy and idiopathic hypersomnia without long sleep time should merge into a single condition."
In a recent interview Karel Šonka said that the ICSD3 new combined Idiopathic Hypersomnia "seems to be defined negatively against narcolepsy and secondary and comorbid hypersomnias and encompasses perhaps a variety of different diseases." He explained that it was "this step back in the definition of idiopathic hypersomnia" that led him & Billiard to perform the cluster analysis that determined Polysymptomatic Hypersomnia is not the same disorder as Monosymptomatic Hypersomnia. This analysis correlates very well with previous studies as well as the differences that we see in people's symptoms. We believe these three clusters better represent the different forms of Narcolepsy and Idiopathic Hypersomnia than the three that have been included in the ICSD3.
It should be noted that it is acknowledged in the analysis that the terms “with long sleep time” and “without long sleep time” are inappropriate as patients with both disorders can experience long sleep. There are other symptoms that have been determined that distinctly separate Polysymptomatic & Monosymptomatic Hypersomnia. These names therefore do not simply replace "with and without long sleep". The analysis needs to be read in full to get a complete understanding of how Polysymptomatic differs from Monosymptomatic Hypersomnia.
We have updated our Fact Sheet to better reflect the current research that also correlates with our own data. Click here for a copy of our fact sheet.